PROTAC 20S proteasome subunit β5 degrader 1
PROTAC 20S proteasome subunit β5 degrader 1 (compound 12f) is a potent degrader (DC50 = 0.11 μM in FaDu cells) that induces cell cycle arrest and apoptosis. It is a valuable research tool for studying bortezomib resistance mechanisms in models of pharyngeal carcinoma and multiple myeloma, demonstrating anti-proliferative and anti-migratory effects in vitro.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.
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