SARS-CoV-IN-6
SARS-CoV-IN-6 (Compound 17) is a dual SARS-CoV-1 and SARS-CoV-2 RdRp inhibitor with an IC50 of 7.8 μM against SARS-CoV-2 RdRp. It demonstrates antiviral activity in replicon-based assays with EC50 values of 0.12 μM and 1.47 μM, respectively, and reduces viral N protein expression, supporting its use in coronavirus replication studies.
Product Specifications
CAS Number
2244671-47-2
Field of Research
Infectious Disease & Virology
Smiles
C (N1C[C@@]2 (C=3N (C[C@@] (C2) (C1) [H]) C (=O) C (NCC=4C (=O) N (C) C (=O) N (C) C4) =CC3) [H]) C5=CC=CC=C5
Molecular Formula
C25H29N5O3
Molecular Weight
447.53
Storage Conditions
-20°C
Notes
For research use only.
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