TH9028
TH9028 is a potent and selective small molecule inhibitor of MTHFD2, exhibiting IC50 values of 11 nM, 7.97 nM, 27 nM, and 0.5 nM against MTHFD2, hMTHFD2, MTHFD2L, and MTHFD1, respectively. This compound is a valuable research tool for studying one-carbon metabolism in cancer cell proliferation and tumor growth, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2379556-15-5
Field of Research
Metabolism Research
Purity
97.57% (May vary between batches)
Smiles
N (C (NC1=C (N) NC (N) =NC1=O) =O) C=2C=CC (C (N[C@@H] (CCC=3NN=NN3) C (O) =O) =O) =NC2
Molecular Formula
C16H18N12O5
Molecular Weight
458.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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