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TH9028

TH9028 is a potent and selective small molecule inhibitor of MTHFD2, exhibiting IC50 values of 11 nM, 7.97 nM, 27 nM, and 0.5 nM against MTHFD2, hMTHFD2, MTHFD2L, and MTHFD1, respectively. This compound is a valuable research tool for studying one-carbon metabolism in cancer cell proliferation and tumor growth, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2379556-15-5

Field of Research

Metabolism Research

Purity

97.57% (May vary between batches)

Smiles

N (C (NC1=C (N) NC (N) =NC1=O) =O) C=2C=CC (C (N[C@@H] (CCC=3NN=NN3) C (O) =O) =O) =NC2

Molecular Formula

C16H18N12O5

Molecular Weight

458.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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