MK-3207
MK-3207 is a potent, orally bioavailable CGRP receptor antagonist with sub-nanomolar affinity (Ki = 0.024 nM) for the human receptor and high selectivity. It effectively blocks CGRP-induced dermal vasodilation in vivo, making it a valuable research tool for studying migraine pathophysiology and neurogenic inflammation in preclinical models.
Product Specifications
CAS Number
957118-49-9
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1[C@@]2 (C=3C (N1) =NC=CC3) CC=4C (C2) =CC=C (NC (CN5[C@@H] (CNC6 (C5=O) CCCC6) C7=CC (F) =CC (F) =C7) =O) C4
Molecular Formula
C31H29F2N5O3
Molecular Weight
557.59
Storage Conditions
-20°C
Notes
For research use only.
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