β-catenin-IN-4
Product Specifications
UNSPSC Description
β-catenin-IN-4 (Compound 39) is a β-catenin inhibitor with a Ki of 0.64 μM. β-catenin-IN-4 reduces the protein expression levels of cyclin D1 and c-Myc[1].
Target Antigen
β-catenin
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/β-catenin-in-4.html
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C(NC1=CC=C(C=C1)OC(F)(F)F)=O)CCC(O)=O)[C@@H](NC([C@@H](NC(C2=CC3=C(N2)C=CC(Cl)=C3)=O)CC4=CC=C5C=CC=CC5=C4)=O)CC(O)=O
Molecular Weight
796.14
References & Citations
[1]McCoy MA, et al. Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale. J Med Chem. 2022 May 26;65(10):7246-7261.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147651/β-catenin-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147651/β-catenin-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2353536-67-9
Available Sizes
Curated Selection
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