SMARCA2-IN-7
SMARCA2-IN-7 (compound 12) is a potent dual BRM (SMARCA2) and BRG1 (SMARCA4) inhibitor with sub-5 nM IC50 values. It demonstrates anti-proliferative activity in cellular assays, including in SKMEL5 and H1299 cell lines. This molecule is a valuable chemical probe for researching SWI/SNF chromatin remodeling complexes in oncology and epigenetics.
Product Specifications
CAS Number
2270879-43-9
Field of Research
Neuroscience
Smiles
O=C (NC=1SN=C (C1) C (F) F) NC2=CC (Cl) =NC=C2CO
Molecular Formula
C11H9ClF2N4O2S
Molecular Weight
334.73
Storage Conditions
-20°C
Notes
For research use only.
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