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SMARCA2-IN-7

SMARCA2-IN-7 (compound 12) is a potent dual BRM (SMARCA2) and BRG1 (SMARCA4) inhibitor with sub-5 nM IC50 values. It demonstrates anti-proliferative activity in cellular assays, including in SKMEL5 and H1299 cell lines. This molecule is a valuable chemical probe for researching SWI/SNF chromatin remodeling complexes in oncology and epigenetics.

Product Specifications

CAS Number

2270879-43-9

Field of Research

Neuroscience

Smiles

O=C (NC=1SN=C (C1) C (F) F) NC2=CC (Cl) =NC=C2CO

Molecular Formula

C11H9ClF2N4O2S

Molecular Weight

334.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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