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GPS1573

GPS1573 is a potent and selective non-competitive antagonist of the melanocortin 2 receptor (MC2R), inhibiting ACTH-stimulated signaling with an IC50 of 66 nM. Its high selectivity makes it a valuable research tool for studying MC2R function in models of Cushing's disease and adrenal disorders, applicable in both in vitro and in vivo experimental systems.

Product Specifications

CAS Number

2445822-54-6

Smiles

C ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (N[C@H] (C (N[C@H] (C (N[C@H] (C (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] (CCCNC (=N) N) C (N) =O) =O) CCCNC (=N) N) =O) CCCCN) =O) CCCCN) =O) =O) C (C) C) =O) C) =O) CCCCN) =O) =O) NC ([C@@H] (NC ([C@H] (NC (=O) [C@H]2N (C ([C@H] (CCCC) N) =O) CCC2) CC3=CC=CC=C3) =O) CCCNC (=N) N) =O) C=4C=5C (NC4) =CC=CC5

Molecular Formula

C86H138N28O14

Molecular Weight

1788.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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