Val-Cit-PAB-DEA-Duo-DM
Val-Cit-PAB-DEA-Duo-DM is a key component for constructing antibody-drug conjugates (ADCs), integrating the protease-cleavable Val-Cit-PAB linker, a DEA spacer, and the potent cytotoxic agent Duocarmycin DM. This conjugate is widely used in research for developing targeted cancer therapies and has been evaluated in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
CAS Number
1698870-53-9
Field of Research
Signal Transduction
Smiles
C (Cl) [C@H]1C2=C (N (C (=O) C3=CC=4C (N3) =CC=C (OCCN (C) C) C4) C1) C=C (OC (N (CCN (C (OCC5=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) CCCNC (N) =O) =O) C=C5) =O) C) C) =O) C=6C2=CC=CC6
Molecular Formula
C50H63ClN10O9
Molecular Weight
983.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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