KS-133
KS-133 is a potent and selective VIPR2 antagonist with IC50 values of 24.8 nM (calcium influx) and 500 nM (cAMP) . It is a valuable research tool for investigating the role of VIPR2 signaling in neuropsychiatric disorders, including schizophrenia, in both cellular and animal models.
Product Specifications
CAS Number
2724212-01-3
Smiles
O=C1[C@]2 (N (C (=O) [C@@H] (NC (C) =O) CSSC[C@]3 (C (=O) N[C@H] (C (N[C@H] (C (N[C@@H] ([C@H] (CC) C) C (N) =O) =O) CC (C) C) =O) CC (=O) NCCCC[C@] (NC (=O) [C@]4 (N (C (=O) [C@H] (CC (C) C) NC (=O) [C@H] (CC5=CC=C (O) C=C5) NC (=O) [C@]6 (N1CCC6) [H]) CCC4) [H]) (C (=O) N[C@@H] (CC7=CC=C (O) C=C7) C (=O) N[C@@H] (CC (C) C) C (=O) N3) [H]) [H]) CCC2) [H]
Molecular Formula
C75H111N15O17S2
Molecular Weight
1558.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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