EGFR/Akt-IN-1

EGFR/Akt-IN-1 (compound 17) is a dual inhibitor of EGFR and Akt, demonstrating IC50 values of 12.89 μM and 10.88 μM in A549 lung carcinoma cells, respectively. It promotes S-phase cell cycle arrest, making it a useful chemical probe for studying oncogenic signaling pathways in cancer research.