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AF3485

AF3485 is a selective mPGES-1 inhibitor that suppresses tumor growth by blocking PGE2 production and downstream EGFR, VEGF, and FGF-2 signaling. It has demonstrated anti-angiogenic and anti-tumor efficacy in both in vitro assays and in vivo A431 xenograft mouse models.

Product Specifications

CAS Number

1195786-61-8

Smiles

O=C (NC1=CC=C2C (=C1) C=3C=CC=CC3N2CCO) C=4C=CC=CC4C (F) (F) F

Molecular Formula

C22H17F3N2O2

Molecular Weight

398.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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