PARP1/2-IN-3
PARP1/2-IN-3 (Compound 29) is a potent, orally bioavailable dual PARP1/2 inhibitor with sub-nanomolar IC50 values. It effectively inhibits the proliferation of various PARP inhibitor-resistant cancer cell lines in vitro and demonstrates in vivo anti-tumor efficacy in mouse models, supporting its use in oncology research.
Product Specifications
CAS Number
3032451-58-1
Field of Research
Cell Biology
Smiles
O=C1NN=C (C=2C=CC=CC12) CC3=CC=C (F) C (=C3) C (=O) N4CC5=NN=C (C=6OC (=CC6) C) N5CC4
Molecular Formula
C26H21FN6O3
Molecular Weight
484.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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