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SDUY038

SDUY038 is a potent, orally bioavailable SHP2 conformational inhibitor with a KD of 0.29 μM. It exhibits broad-spectrum antitumor activity in vitro by suppressing pERK signaling (IC50= 7-24 μM) and demonstrates an oral half-life of 3.95 hours in vivo, supporting its use in cancer research.

Product Specifications

CAS Number

2892720-11-3

Smiles

O=C (C=1OC (SC=2C=CC=C (Cl) C2Cl) =CC1) N3CCC (N) (C) CC3

Molecular Formula

C17H18Cl2N2O2S

Molecular Weight

385.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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