SDUY038
SDUY038 is a potent, orally bioavailable SHP2 conformational inhibitor with a KD of 0.29 μM. It exhibits broad-spectrum antitumor activity in vitro by suppressing pERK signaling (IC50= 7-24 μM) and demonstrates an oral half-life of 3.95 hours in vivo, supporting its use in cancer research.
Product Specifications
CAS Number
2892720-11-3
Smiles
O=C (C=1OC (SC=2C=CC=C (Cl) C2Cl) =CC1) N3CCC (N) (C) CC3
Molecular Formula
C17H18Cl2N2O2S
Molecular Weight
385.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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