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USP1-IN-10

USP1-IN-10 (compound 2) is a potent tricyclic USP1 inhibitor with an IC50 of 7.6 nM, and it reduces MDA-MB-436 cell viability with an IC50 of 21.58 nM. This inhibitor is a valuable chemical probe for studying USP1 function in DNA damage repair pathways and BRCA-deficient cancers in vitro.

Product Specifications

CAS Number

2857051-98-8

Field of Research

Epigenetics & Chromatin

Smiles

FC (F) (F) C=1N=C (C=2C=CC (=CC2) CN3C4=NC (=NC=C4N5C=NC=C53) C=6C (=NC=NC6C7CC7) OC) N (C1) C

Molecular Formula

C27H22F3N9O

Molecular Weight

545.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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