USP1-IN-10
USP1-IN-10 (compound 2) is a potent tricyclic USP1 inhibitor with an IC50 of 7.6 nM, and it reduces MDA-MB-436 cell viability with an IC50 of 21.58 nM. This inhibitor is a valuable chemical probe for studying USP1 function in DNA damage repair pathways and BRCA-deficient cancers in vitro.
Product Specifications
CAS Number
2857051-98-8
Field of Research
Epigenetics & Chromatin
Smiles
FC (F) (F) C=1N=C (C=2C=CC (=CC2) CN3C4=NC (=NC=C4N5C=NC=C53) C=6C (=NC=NC6C7CC7) OC) N (C1) C
Molecular Formula
C27H22F3N9O
Molecular Weight
545.52
Storage Conditions
-20°C
Notes
For research use only.
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