LMP7/LMP2-IN-1
LMP7/LMP2-IN-1 (Compound 19) is an orally active dual inhibitor of immunoproteasome subunits LMP2 (IC50=10 nM) and LMP7 (IC50=257 nM) . It has been shown in vivo to reduce antibody production and modulate B-cell populations in immunized mice, supporting its use as a research tool for studying autoimmune conditions.
Product Specifications
CAS Number
3053755-09-9
Field of Research
Immunology & Inflammation, Protein Biochemistry
Smiles
C (N[C@H] (B (O) O) C1CCCCC1) (=O) C2=CN (N=N2) C3CCCCC3
Molecular Formula
C16H27BN4O3
Molecular Weight
334.22
Storage Conditions
-20°C
Notes
For research use only.
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