RPS6-IN-1

RPS6-IN-1 (Compound 22o) is a research compound that acts as a multi-target anticancer agent by inhibiting RPS6 phosphorylation and the PI3K-Akt-mTOR pathway. This activity induces apoptosis, inhibits cell migration, and triggers autophagy along with mitochondrial and ER stress, as demonstrated in vitro. It is noted for its low systemic toxicity profile in research models.