Val-Cit-PAB-Exatecan TFA
Val-Cit-PAB-Exatecan TFA is a cleavable linker-payload complex for constructing antibody-drug conjugates (ADCs) . It incorporates the potent topoisomerase I inhibitor DX-8951, enabling targeted delivery and release for the research of novel anticancer therapies in both cellular and animal models.
Product Specifications
CAS Number
2928571-44-0
Field of Research
Immunology & Inflammation; Pharmacology & Drug Discovery
Smiles
C (C (O) =O) (F) (F) F.N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) CCCNC (N) =O) =O) C=C1) =O) [C@@H]2C3=C4C (C=5N (C4) C (=O) C6=C (C5) [C@] (CC) (O) C (=O) OC6) =NC=7C3=C (CC2) C (C) =C (F) C7
Molecular Formula
C45H50F4N8O11
Molecular Weight
954.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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