CDK4/6-IN-21 maleate
CDK4/6-IN-21 maleate (I-52) is a highly potent and selective dual inhibitor of CDK4 (IC50=3.88 nM) and CDK6 (IC50=3.31 nM) . It demonstrates robust antitumor activity in cellular assays and is a valuable chemical probe for researching cell cycle dysregulation in cancers both in vitro and in vivo.
Product Specifications
CAS Number
2765997-88-2
Field of Research
Signal Transduction
Purity
99.98% (May vary between batches)
Smiles
C (=C\C (O) =O) \C (O) =O.CC=1N (C=2C (N1) =C (F) C=C (C2) C3=NC (NC=4N=C5C (=CC4) CN (CCN (C) C) CC5) =NC=C3F) C6CC6
Molecular Formula
C31H34F2N8O4
Molecular Weight
620.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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