VEGFR-2/AKT-IN-1

VEGFR-2/AKT-IN-1 (compound 17) is a dual-target inhibitor with IC50 values of 0.164 μM for VEGFR-2 and 0.452 μM for AKT. This small molecule demonstrates antitumor activity and is a useful research tool for investigating angiogenesis and PI3K/AKT signaling pathways in cancer models, both in vitro and in vivo.