Akt/mTOR-IN-1

Akt/mTOR-IN-1 (Compound 8r) is a dual AKT/mTOR pathway inhibitor with an IC50 of 0.8 μM, demonstrating anticancer activity in non-small cell lung cancer (NSCLC) research. It modulates key proteins, reducing Caspase 3 and elevating Cyclin B1, to induce both autophagy and apoptosis in cellular models.