Brimarafenib
Brimarafenib is a selective RAF dimerization inhibitor that potently targets BRAF and CRAF, including various BRAF mutations and fusions. It is utilized in preclinical research for studying MAPK pathway-driven solid tumors, such as colorectal and pancreatic cancers, in both in vitro and in vivo models.
Product Specifications
CAS Number
1643326-82-2
Product Name Alternative
Brimarafenib, Brimarafenibum, BGB3245, BGB-3245, BGB 245, BGB245
Field of Research
Signal Transduction
Purity
98.32% (May vary between batches)
Smiles
N (C (NC1=C (F) C=C (F) C (F) =C1) =O) [C@H]2[C@]3 ([C@@]2 (OC=4C3=CC (OC5=C6C (NC=C5) =NC (=O) CC6) =CC4) [H]) [H]
Molecular Formula
C24H17F3N4O4
Molecular Weight
482.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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