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YTR107

YTR107 is a small molecule radiosensitizer that targets nucleophosmin 1 (NPM1), disrupting its pentamerization. This action impairs NPM1 recruitment to DNA damage sites and inhibits double-strand break repair, thereby enhancing radiation-induced cell death in cancer research models, both in vitro and in vivo.

Product Specifications

CAS Number

1207615-74-4

Smiles

N#CC1=CC=C (C=C1) CN2C=C (C=C3C (=O) NC (=O) NC3=O) C=4C=CC=CC42

Molecular Formula

C21H14N4O3

Molecular Weight

370.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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