YTR107
YTR107 is a small molecule radiosensitizer that targets nucleophosmin 1 (NPM1), disrupting its pentamerization. This action impairs NPM1 recruitment to DNA damage sites and inhibits double-strand break repair, thereby enhancing radiation-induced cell death in cancer research models, both in vitro and in vivo.
Product Specifications
CAS Number
1207615-74-4
Smiles
N#CC1=CC=C (C=C1) CN2C=C (C=C3C (=O) NC (=O) NC3=O) C=4C=CC=CC42
Molecular Formula
C21H14N4O3
Molecular Weight
370.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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