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SH-E4A-66

SH-E4A-66 is a covalent protein ligator (C2-COUPLr) built on a carbazole scaffold, utilizing a non-acrylamide/chloroacetamide cysteine-targeting warhead. It binds to and inhibits EML4-ALK kinase activity with EC50 and IC50 values of 1.5 μM and 2.3 μM, respectively, serving as a research tool for studying ALK-driven cancers in cellular models.

Product Specifications

Field of Research

Cardiovascular Research, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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