PD-1/PD-L1-IN-47
PD-1/PD-L1-IN-47 is a small molecule inhibitor with enhanced selectivity for the PD-1/PD-L1 interaction under acidic conditions, such as those found in the tumor microenvironment. This pH-dependent activity, coupled with a favorable toxicity profile, makes it a valuable tool for investigating cancer immunotherapy in both cellular assays and in vivo models.
Product Specifications
CAS Number
1137341-95-7
Field of Research
Cancer Biology; Immunology & Inflammation
Smiles
O (CC (C) C1 (O) CC (=O) OC1) [C@@H]2O[C@H] (COC (/C=C/C3=CC (O) =C (O) C=C3) =O) [C@@H] (O) [C@H] (O) [C@H]2O
Molecular Formula
C22H28O12
Molecular Weight
484.45
Storage Conditions
-20°C
Notes
For research use only.
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