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PD-1/PD-L1-IN-47

PD-1/PD-L1-IN-47 is a small molecule inhibitor with enhanced selectivity for the PD-1/PD-L1 interaction under acidic conditions, such as those found in the tumor microenvironment. This pH-dependent activity, coupled with a favorable toxicity profile, makes it a valuable tool for investigating cancer immunotherapy in both cellular assays and in vivo models.

Product Specifications

CAS Number

1137341-95-7

Field of Research

Cancer Biology; Immunology & Inflammation

Smiles

O (CC (C) C1 (O) CC (=O) OC1) [C@@H]2O[C@H] (COC (/C=C/C3=CC (O) =C (O) C=C3) =O) [C@@H] (O) [C@H] (O) [C@H]2O

Molecular Formula

C22H28O12

Molecular Weight

484.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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