BVB808
BVB808 is a potent and selective JAK2 inhibitor, demonstrating approximately 10-fold selectivity over other JAK family members in vitro. It blocks JAK2-STAT5 signaling, inhibiting proliferation and survival in dependent cell lines, and is a valuable tool for investigating JAK2-driven hematological cancers in preclinical research.
Product Specifications
CAS Number
1414587-22-6
Smiles
N (C=1N=C2N (C=CC2=CN1) C3=CC (F) =C (CN4CCOCC4) C (F) =C3) C5=CC=C (C=C5) N6C[C@@H] (C) N[C@@H] (C) C6
Molecular Formula
C29H33F2N7O
Molecular Weight
533.62
Storage Conditions
-20°C
Notes
For research use only.
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