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BVB808

BVB808 is a potent and selective JAK2 inhibitor, demonstrating approximately 10-fold selectivity over other JAK family members in vitro. It blocks JAK2-STAT5 signaling, inhibiting proliferation and survival in dependent cell lines, and is a valuable tool for investigating JAK2-driven hematological cancers in preclinical research.

Product Specifications

CAS Number

1414587-22-6

Smiles

N (C=1N=C2N (C=CC2=CN1) C3=CC (F) =C (CN4CCOCC4) C (F) =C3) C5=CC=C (C=C5) N6C[C@@H] (C) N[C@@H] (C) C6

Molecular Formula

C29H33F2N7O

Molecular Weight

533.62

Storage Conditions

-20°C

Notes

For research use only.

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