JP-2-249
JP-2-249 is a molecular glue degrader that potently reduces SMARCA2 protein levels at low micromolar concentrations in MV-4-11 cells. This compound is a valuable chemical probe for oncology research, enabling the study of SMARCA2-dependent functions and vulnerabilities in cancer models both in vitro and in vivo.
Product Specifications
CAS Number
3036530-41-0
Field of Research
Cell Biology
Smiles
NC1=C (C=C (N=N1) C2=C (O) C=CC=C2) N3CCN (C (/C=C/C (=O) C4=CC=C (OC) C=C4) =O) CC3
Molecular Formula
C25H25N5O4
Molecular Weight
459.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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