JP-2-249
JP-2-249 is a molecular glue degrader that potently reduces SMARCA2 protein levels at low micromolar concentrations in MV-4-11 cells. This compound is a valuable chemical probe for oncology research, enabling the study of SMARCA2-dependent functions and vulnerabilities in cancer models both in vitro and in vivo.
Product Specifications
CAS Number
3036530-41-0
Field of Research
Cell Biology
Smiles
NC1=C (C=C (N=N1) C2=C (O) C=CC=C2) N3CCN (C (/C=C/C (=O) C4=CC=C (OC) C=C4) =O) CC3
Molecular Formula
C25H25N5O4
Molecular Weight
459.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS637571-01 0.05 mg
LEDGF, Recombinant Human (Lens Epithelium-derived Growth Factor, Transcriptional Coactivator p75/p52, PSIP1, PC4 and SFRS1-interacting Protein, PSIP2, DFS70, Dense Fine Speckles 70kD Protein, PAIP, CLL-associated Antigen KW-7)
Sign In for Pricing
View Details 
MBS637571-02 5x 0.05 mg
LEDGF, Recombinant Human (Lens Epithelium-derived Growth Factor, Transcriptional Coactivator p75/p52, PSIP1, PC4 and SFRS1-interacting Protein, PSIP2, DFS70, Dense Fine Speckles 70kD Protein, PAIP, CLL-associated Antigen KW-7)
Sign In for Pricing
View Details 
TL709816V 500 µL Each
Casr Rat shRNA Lentiviral Particle (Locus ID 24247)
Sign In for Pricing
View Details MAB495C 0.2 mL (200 µg)
Tubulin, beta subunit Antibody, Concentrate
Sign In for Pricing
View Details