AZ683

AZ683 is a potent and selective 3-amino-4-anilinoquinoline inhibitor of CSF1R (Ki=8 nM) with high oral bioavailability. Its radiolabeled analog, [11C]AZ683, serves as a PET tracer, enabling non-invasive imaging of CSF1R in preclinical models for oncology and neuroinflammation research.