AZ683
AZ683 is a potent and selective 3-amino-4-anilinoquinoline inhibitor of CSF1R (Ki=8 nM) with high oral bioavailability. Its radiolabeled analog, [11C]AZ683, serves as a PET tracer, enabling non-invasive imaging of CSF1R in preclinical models for oncology and neuroinflammation research.
Product Specifications
CAS Number
953798-95-3
Field of Research
Signal Transduction
Smiles
O=C (N) C1=CN=C2C=C (OCC) C (=CC2=C1NC3=CC=C (F) C=C3F) N4CCN (C) CC4
Molecular Formula
C23H25F2N5O2
Molecular Weight
441.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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