PI4KIIIbeta-IN-10
PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC50 of 3.6 nM.
Product Specifications
CAS Number
[1881233-39-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PI3K; PI4K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/PI4KIIIbeta-IN-10.html
Purity
99.84
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C2=C(C)N=C(NC(C(C)(C)C)=O)S2)C=C1S(NC3=CC=C(O)C=C3)(=O)=O
Molecular Formula
C22H25N3O5S2
Molecular Weight
475.58
Precautions
H302, H315, H319, H335
References & Citations
[1]Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. J Med Chem. 2016 Mar 10;59 (5) :1830-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI4KIIIα; PI4KIIIβ
Available Sizes
Curated Selection
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