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LL-K12-18

LL-K12-18 is a molecular glue that stabilizes the interaction between CDK12 and DDB1, leading to Cyclin K degradation. This compound suppresses transcription and proliferation in cancer cells, serving as a valuable chemical probe for studying CDK12/cyclin K biology and targeted protein degradation in oncology research.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

98.08% (May vary between batches)

Smiles

CCN1C2=NC (N3CCN (C (CN (CC) CC) =O) CC3) =NC (NCC4=NC5=CC (Cl) =C (Cl) C=C5N4) =C2N=C1

Molecular Formula

C25H32Cl2N10O

Molecular Weight

559.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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