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TX-2552

TX-2552 is a potent and orally bioavailable TDP1 inhibitor (IC50 = 0.62 μM) . It synergizes with topoisomerase I poisons like topotecan, enhancing DNA damage and antitumor efficacy in both cellular assays and murine cancer models, supporting its investigation in oncology research.

Product Specifications

CAS Number

2446767-14-0

Smiles

O=C1C=C (C=2C (=CC (OC/C=C (/CCC=C (C) C) \C) =CC2) O1) C3=CC=C (F) C=C3

Molecular Formula

C25H25FO3

Molecular Weight

392.46

Storage Conditions

-20°C

Notes

For research use only.

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