TX-2552
TX-2552 is a potent and orally bioavailable TDP1 inhibitor (IC50 = 0.62 μM) . It synergizes with topoisomerase I poisons like topotecan, enhancing DNA damage and antitumor efficacy in both cellular assays and murine cancer models, supporting its investigation in oncology research.
Product Specifications
CAS Number
2446767-14-0
Smiles
O=C1C=C (C=2C (=CC (OC/C=C (/CCC=C (C) C) \C) =CC2) O1) C3=CC=C (F) C=C3
Molecular Formula
C25H25FO3
Molecular Weight
392.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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