Segigratinib hydrochloride
Segigratinib hydrochloride (3D185) is a potent small molecule inhibitor of FGFR1/2/3 and CSF-1R with low nanomolar IC50 values. It demonstrates anti-tumor activity in preclinical research, applicable for studying oncogenic signaling, tumor microenvironment, and therapeutic efficacy in both cellular and animal models.
Product Specifications
CAS Number
2847066-15-1
Smiles
Cl.O=C (NC1=NNC=2N=C (C=CC12) C=3C (Cl) =C (OC) C=C (OC) C3Cl) C4=CC=C (C=C4) N5CCNC (C) (C) C5
Molecular Formula
C27H29Cl3N6O3
Molecular Weight
591.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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