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Segigratinib hydrochloride

Segigratinib hydrochloride (3D185) is a potent small molecule inhibitor of FGFR1/2/3 and CSF-1R with low nanomolar IC50 values. It demonstrates anti-tumor activity in preclinical research, applicable for studying oncogenic signaling, tumor microenvironment, and therapeutic efficacy in both cellular and animal models.

Product Specifications

CAS Number

2847066-15-1

Smiles

Cl.O=C (NC1=NNC=2N=C (C=CC12) C=3C (Cl) =C (OC) C=C (OC) C3Cl) C4=CC=C (C=C4) N5CCNC (C) (C) C5

Molecular Formula

C27H29Cl3N6O3

Molecular Weight

591.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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