DBCO-PEG3-Glu-Val-Cit-PABC-MMAE
DBCO-PEG3-Glu-Val-Cit-PABC-MMAE is a cleavable drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs) . It incorporates the cytotoxic payload MMAE and is widely used in ADC research for targeted cancer therapy, enabling both in vitro cytotoxicity studies and in vivo efficacy evaluations in preclinical models.
Product Specifications
CAS Number
2861998-23-2
Field of Research
Cell Biology
Smiles
C (CCC (NCCOCCOCCOCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (NC1=CC=C (COC (N ([C@H] (C (N[C@H] (C (N ([C@H] ([C@@H] (CC (=O) N2[C@] ([C@@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C3=CC=CC=C3) C) =O) C) OC) (CCC2) [H]) OC) [C@H] (CC) C) C) =O) C (C) C) =O) [C@@H] (C) C) C) =O) C=C1) =O) CCCNC (N) =O) =O) C (C) C) =O) CCC (O) =O) =O) =O) (=O) N4C=5C (C#CC=6C (C4) =CC=CC6) =CC=CC5
Molecular Formula
C90H129N13O21
Molecular Weight
1729.06
Storage Conditions
-20°C
Notes
For research use only.
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