EphB6, Mouse (HEK293, His)

EphB6 Protein, a kinase-defective receptor, binds ephrin-B1 and ephrin-B2, influencing cell adhesion and migration with nuanced effects. Its interaction with ephrin-B2 inhibits JNK activation, T-cell receptor-induced IL-2 secretion, and CD25 expression. EphB6 also interacts with CBL, EPHB1, and ligand-independently with FYN, highlighting its intricate role in cellular signaling pathways. EphB6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphB6 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB6 Protein, Mouse (HEK293, His) is 555 a.a., with molecular weight of ~66 kDa.

LEEVLLDTTG ETSEIGWLTY PPGGWDEVSV LDDQRRLTRT FEACHVAGLP PGSGQDNWLQ THFVERRGAQ RAHIRLHFSV RACSSLGVSG GTCRETFTLY YRQADEPDGP DSIAAWHLKR WTKVDTIAAD ESFPASSSSS SWAVGPHRTG QRVGLQLNVK ERSFGPLTQR GFYVAFQDTG ACLALVAVKL FSYTCPSVLR AFASFPETQA SGAGGASLVA AVGTCVAHAE PEEDGVGGQA GGSPPRLHCN GEGRWMVAVG GCRCQPGHQP ARGDKLCQAC PEGSYKALAG NVPCSPCPAR SHSPDPAAPV CPCLQGFYRA SSDPPEAPCT GPPSAPRELW FEVQGSALML HWRLPQELGG RGDLLFNVVC KECGGHGEPS SGGMCRRCRD EVHFDPRQRG LTESRVLVGG LRAHVPYILE VQAVNGVSEL SPDPPQAAAI NVSTSHEVPS AVPVMHQVSR AANSITVSWP QPEQTNGNIL DYQLRYYDQA EDESHSFTMT SETNTATVTR LSPGHIYGFQ VRARTAAGHG PYGGKVYFQT LPQGELSSQL PEKLS