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PROTAC erf3a Degrader-2

PROTACerf3a Degrader-2 (C59) is an orally bioavailable small molecule that degrades eRF3a (GSPT1) and downregulates SRD5A3, inhibiting cancer cell proliferation. It is used in vitro and in vivo research for studying prostate, ovarian, liver, cervical, leukemia, and breast cancers.

Product Specifications

CAS Number

3033871-15-4

Smiles

C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) [C@@] (CC3) (NC (=O) C=C4) [H]) (CC1) [H]) [H]) (CC[C@@H]2C (NC5=CC (N[C@H]6C[C@H] (NC7=C8C (C (=O) N (C8=O) C9C (=O) NC (=O) CC9) =CC=C7) CCC6) =CC=C5) =O) [H]

Molecular Formula

C44H52N6O6

Molecular Weight

760.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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