Sutetinib
Sutetinib is a potent, orally active tyrosine kinase inhibitor targeting VEGFR, PDGFR, and cKIT with low nanomolar Ki values. It suppresses endothelial and fibroblast cell proliferation, migration, and tube formation, demonstrating antitumor activity in vitro. Its research applications include studying angiogenesis and tumor growth in both cellular and animal models.
Product Specifications
CAS Number
1259519-20-4
Smiles
N (C=1C2=C (C=C (OCC) C (NC (/C=C/CN (C) C) =O) =C2) N=CC1C#N) C3=CC (C#C) =CC=C3
Molecular Formula
C26H25N5O2
Molecular Weight
439.51
Storage Conditions
-20°C
Notes
For research use only.
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