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Sutetinib

Sutetinib is a potent, orally active tyrosine kinase inhibitor targeting VEGFR, PDGFR, and cKIT with low nanomolar Ki values. It suppresses endothelial and fibroblast cell proliferation, migration, and tube formation, demonstrating antitumor activity in vitro. Its research applications include studying angiogenesis and tumor growth in both cellular and animal models.

Product Specifications

CAS Number

1259519-20-4

Smiles

N (C=1C2=C (C=C (OCC) C (NC (/C=C/CN (C) C) =O) =C2) N=CC1C#N) C3=CC (C#C) =CC=C3

Molecular Formula

C26H25N5O2

Molecular Weight

439.51

Storage Conditions

-20°C

Notes

For research use only.

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