PolQi1
PolQi1 is a potent and selective DNA polymerase theta (PolΘ) inhibitor with a 2 nM IC50. It is a valuable research tool for studying PolΘ's role in DNA repair, particularly in cancer contexts, and has shown utility in both in vitro and in vivo studies exploring targeted cancer therapies.
Product Specifications
CAS Number
2607139-80-8
Field of Research
Cell Biology, Molecular Biology
Purity
98.97% (May vary between batches)
Solubility
DMSO:3 mg/mL (6.68 mM)
Smiles
C (N (C) C1=C (F) C (Cl) =C (F) C=C1) (=O) [C@H]2N (C (=O) NC2) C3=CC (C (F) (F) F) =CC (C) =N3
Molecular Formula
C18H14ClF5N4O2
Molecular Weight
448.77
Storage Conditions
-20°C
Notes
For research use only.
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