Anticonvulsant agent 5

This small molecule research compound is a dual-affinity ligand for GABAA and NaV1.3 receptors. It demonstrates anticonvulsant efficacy in a murine psychomotor seizure model (ED50 107 mg/kg) and offers neuroprotection against kainic acid-induced excitotoxicity (IC50 113 μM), supported by its blood-brain barrier permeability for central nervous system studies.