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CMPD101 hydrochloride

CMPD101 hydrochloride is a potent, cell-permeable inhibitor of GRK2 (IC50=18 nM) and GRK3 (IC50=5.4 nM), with additional activity against ROCK-2 and PKCα. This tool compound is utilized in cardiovascular and oncology research to investigate GPCR signaling pathways in both cellular and animal models.

Product Specifications

CAS Number

1941168-71-3

Smiles

Cl.O=C (NCC=1C=CC=CC1C (F) (F) F) C=2C=CC=C (C2) NCC3=NN=C (C=4C=CN=CC4) N3C

Molecular Formula

C24H22ClF3N6O

Molecular Weight

502.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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