8-NBD-cGMP
8-NBD-cGMP is a membrane-permeable, fluorescent cGMP analog that selectively activates cGMP-dependent protein kinase I isozymes (PKG Iα and Iβ) . Its fluorescence is quenched in aqueous solution but intensifies in hydrophobic environments like protein binding sites, making it a valuable probe for studying PKG signaling dynamics in vitro.
Product Specifications
CAS Number
115993-88-9
Smiles
O=C (N=C (N1) N) C2=C1N ([C@H]3[C@@H] ([C@@]4 ([H]) [C@] (COP (O) (O4) =O) ([H]) O3) O) C (SCCNC5=CC=C ([N+] ([O-]) =O) C6=NON=C56) =N2
Molecular Formula
C18H18N9O10PS
Molecular Weight
583.43
Storage Conditions
-20°C
Notes
For research use only.
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